In the present work, an inductively coupled plasma mass spectrometer operating in single quadrupole was performed for determination of some rare-earth elements including La, Sm, Eu, Tl, and U in rice. The samples were prepared by microwave digestion with nitric acid. The fortifications of rice samples at 3 levels were studied in order to check the accuracy of the proposed method. The experiment was performed under the internal standard method with the coefficient of determination higher than 0.9990. The average recoveries of all elements were higher than 92% with the standard deviation less than 4.5.